ZNF19

Across TCGA cell cohorts, ZNF19 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF19-associated genes across cancer lineages are A4GNT, OR10A5, and PLCZ1. Each is linked with ZNF19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF19-to-partner and partner-to-ZNF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A4GNT grouped by ZNF19-low versus ZNF19-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF19→partner) and Y-score (partner→ZNF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	A4GNT →	+0.058	+3.252	.002	<.001	3	1
LARGE_INTESTINE	OR10A5 →	+0.046	+2.672	<.001	.004	3	1
BLOOD_Lymphoma	PLCZ1 →	+0.152	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	OR6X1 →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	MAGEL2 →	+0.029	+5.643	<.001	.002	3	1
SKIN	OR2T29 →	+0.016	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

A4GNT by ZNF19 expression — LARGE_INTESTINE

Explore this box plot interactively →