ZNF182

Across TCGA patient cohorts, ZNF182 mutation is significantly associated with the RNA expression of many other genes, with 3,736 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF182-associated genes across cancer lineages are MGAT2P2, KCNJ15, and RPUSD2. Each is linked with ZNF182 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF182-to-partner and partner-to-ZNF182 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MGAT2P2 grouped by ZNF182-low versus ZNF182-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF182→partner) and Y-score (partner→ZNF182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MGAT2P2 →	+0.029	+8.057	<.001	.005	3	2
UCEC	KCNJ15 →	-0.692	-3.076	.001	<.001	3	2
UCEC	RPUSD2 →	+0.312	+2.544	<.001	<.001	3	2
UCEC	PRELID1 →	+0.301	+1.539	.003	.002	3	2
UCEC	POLDIP2 →	+0.246	+1.939	.009	<.001	3	2
UCEC	PKM →	+0.437	+1.906	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,736 associations by consensus.

MGAT2P2 by ZNF182 expression — BRCA

Explore this box plot interactively →