ZNF182

Across TCGA pan-cancer cohorts, ZNF182 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated ZNF182 data layer compared with 5 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ZNF182 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF182 expression acts as an unfavorable survival marker, although some lineages such as BLCA and GBM show a favorable association.

BLCA, LIHC, and UVM are the cancer types where ZNF182 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Quartile	All	0.519	0.259	<.001	58	view →
LIHC	OS	Median	All	0.608	0.764	<.001	56	view →
UVM	DFS	Quartile	III,IV	0.182	0.910	<.001	55	view →
KIRP	DFS	Median	All	0.360	0.712	.001	54	view →
KIRC	DFS	Tertile	II,III,IV	0.384	0.667	.001	39	view →
LGG	OS	Tertile	All	0.335	0.589	<.001	35	view →
MESO	DFS	Median	All	0.301	0.471	.005	27	view →
LUSC	DFS	Median	III,IV	0.181	0.834	.001	23	view →
GBM	DFS	Tertile	All	0.497	0.183	<.001	19	view →
READ	OS	Tertile	IV	0.850	0.352	.007	19	view →
SKCM	DFS	Quartile	All	0.253	0.142	.001	15	view →
KICH	OS	Median	II,III,IV	0.787	0.969	.004	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

ZNF182–BLCA (OS)

Open the BLCA breakdown →