ZNF182

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF182 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZNF182-associated genes across cancer lineages are CD300LG, GPR149, and TDRD15. Each is linked with ZNF182 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF182-to-partner and partner-to-ZNF182 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300LG grouped by ZNF182-low versus ZNF182-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF182→partner) and Y-score (partner→ZNF182) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTCD300LG →+0.035+3.758<.001.00731
BREASTGPR149 →+0.036+4.312<.001.00131
BREASTTDRD15 →+0.005+4.312<.001.00131
BREASTSPEM3 →+0.070+4.209<.001.00231
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD300LG by ZNF182 expression — BREAST

Box plot of CD300LG in ZNF182-low vs ZNF182-high samples in BREAST.

Explore this box plot interactively →

Exploration