Across TCGA patient cohorts, ZNF181 protein abundance is significantly associated with the RNA expression of many other genes, with 427 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF181-associated genes across cancer lineages are KIAA0930, SPRTN, and PCYT1B. Each is linked with ZNF181 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF181-to-partner and partner-to-ZNF181 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF181→partner) and Y-score (partner→ZNF181) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KIAA0930 →	-1.023	-0.620	.003	<.001	3	1
GBM	SPRTN →	-0.633	-0.451	<.001	.002	3	1
GBM	PCYT1B →	-1.833	-0.620	<.001	<.001	3	1
GBM	HTR2A →	-1.801	-0.442	.009	.003	3	1
GBM	HERC1 →	-0.642	-0.442	.008	.003	3	1
GBM	PPP3CB →	-0.994	-0.442	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 427 associations by consensus.

Exploration

ZNF181 survival (RNA) · tumor vs normal (RNA) · all ZNF181 data types