ZNF181

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF181 mutation is significantly associated with the RNA expression of many other genes, with 896 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF181-associated genes across cancer lineages are BLOC1S2P1, VEZF1P1, and RNU6-218P. Each is linked with ZNF181 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF181-to-partner and partner-to-ZNF181 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF181→partner) and Y-score (partner→ZNF181) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCABLOC1S2P1 →+0.161+5.441<.001.00532
UCECVEZF1P1 →+0.124+2.489<.001<.00132
UCECRNU6-218P →+0.447+1.667<.001.00532
OVSLC25A1P4 →+0.094+4.991<.001.00932
BLCARNU7-128P →+1.276+3.982<.001.00632
SKCMRNU6-252P →+0.292+4.385<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 896 associations by consensus.

Exploration