ZNF180

Across TCGA patient cohorts, ZNF180 protein abundance is significantly associated with the RNA expression of many other genes, with 3,592 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF180-associated genes across cancer lineages are MIR6757, JAK3, and TMIGD3. Each is linked with ZNF180 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF180-to-partner and partner-to-ZNF180 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF180 versus MIR6757 in LSCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF180→partner) and Y-score (partner→ZNF180) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MIR6757 →	+1.310	+0.787	.008	.002	3	2
GBM	JAK3 →	-0.926	-0.555	<.001	<.001	3	2
GBM	TMIGD3 →	-1.432	-0.861	<.001	<.001	3	2
LUAD	ERG28 →	+0.723	+0.883	.004	.003	3	2
LUAD	PTPN7 →	-0.915	-1.004	.003	.001	3	2
GBM	FCGR1B →	-1.017	-0.925	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,592 associations by consensus.

ZNF180 vs MIR6757 — LSCC

Explore this scatter interactively →