Across TCGA patient cohorts, ZNF165 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF165-associated genes across cancer lineages are ERK2, MAPK_pT202_Y204, and STAT3_pY705. Each is linked with ZNF165 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF165-to-partner and partner-to-ZNF165 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF165→partner) and Y-score (partner→ZNF165) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.211	+2.321	.015	.033	3	2
UCEC	MAPK_pT202_Y204 →	-0.450	-2.321	.033	.034	3	2
UCEC	STAT3_pY705 →	-0.394	-2.311	<.001	.034	3	2
UCEC	Caspase-8 →	-0.238	-3.295	.036	.009	3	2
UCEC	EGFR_pY1068 →	-0.249	-2.999	.027	.035	3	1
UCEC	GSK-3_pS9 →	-0.482	-3.169	.008	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

ZNF165 survival (RNA) · tumor vs normal (RNA) · all ZNF165 data types