ZNF142

Across TCGA patient cohorts, ZNF142 mutation is significantly associated with the RNA expression of many other genes, with 4,801 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF142-associated genes across cancer lineages are PSMA3, XPNPEP1, and MAIP1. Each is linked with ZNF142 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF142-to-partner and partner-to-ZNF142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMA3 grouped by ZNF142-low versus ZNF142-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF142→partner) and Y-score (partner→ZNF142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PSMA3 →	+0.342	+2.636	.009	.005	3	4
SKCM	XPNPEP1 →	+0.413	+2.009	.003	.005	3	4
UCEC	MAIP1 →	+0.350	+1.769	.008	.003	3	4
UCEC	CDKN3 →	+0.641	+2.332	<.001	<.001	3	4
COAD	PSRC1 →	+0.566	+3.525	<.001	.002	3	4
UCEC	TTF2 →	+0.478	+1.595	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,801 associations by consensus.

PSMA3 by ZNF142 expression — SKCM

Explore this box plot interactively →