ZNF142

Across TCGA patient cohorts, ZNF142 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF142-associated genes across cancer lineages are eEF2, GAPDH, and ACVRL1. Each is linked with ZNF142 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF142-to-partner and partner-to-ZNF142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ZNF142-low versus ZNF142-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF142→partner) and Y-score (partner→ZNF142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eEF2 →	+0.359	+3.169	.005	.018	3	3
COAD	GAPDH →	+0.714	+3.169	.001	.017	3	2
COAD	ACVRL1 →	-0.254	-2.987	.019	.035	2	3
COAD	Myosin-IIa_pS1943 →	+0.347	+3.000	.022	.034	3	2
COAD	PCNA →	+0.353	+2.467	.001	.011	3	2
COAD	Rad50 →	-0.435	-3.321	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

eEF2 by ZNF142 expression — COAD

Explore this box plot interactively →