ZNF142

Across TCGA cell cohorts, ZNF142 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,899 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF142-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Regulation of protein localization to centrosome, and Pre-mRNA catabolic process. Each is linked with ZNF142 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF142-to-partner and partner-to-ZNF142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Subtelomeric heterochromatin formation grouped by ZNF142-low versus ZNF142-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF142→partner) and Y-score (partner→ZNF142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Subtelomeric heterochromatin formation →	+0.139	+1.047	<.001	<.001	3	18
LUNG_SCLC	Regulation of protein localization to centrosome →	+0.135	+0.604	<.001	<.001	3	17
BONE	Pre-mRNA catabolic process →	+0.225	+1.173	<.001	<.001	3	17
PANCREAS	Microtubule polymerization →	+0.104	+0.943	<.001	<.001	3	17
BONE	Chromosome separation →	+0.145	+0.931	<.001	<.001	3	17
BONE	RNA export from nucleus →	+0.116	+1.082	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,899 associations by consensus.

Subtelomeric heterochromatin formation by ZNF142 expression — URINARY_TRACT

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