ZNF142

Across TCGA cell cohorts, ZNF142 mutation is significantly associated with the RNA expression of many other genes, with 1,372 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF142-associated genes across cancer lineages are GFRA4, BHLHE23, and JOSD1. Each is linked with ZNF142 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF142-to-partner and partner-to-ZNF142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GFRA4 grouped by ZNF142-low versus ZNF142-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF142→partner) and Y-score (partner→ZNF142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	GFRA4 →	+0.016	+5.614	<.001	.002	3	2
BLOOD_Leukemia	BHLHE23 →	+0.969	+2.784	<.001	.001	3	2
BLOOD_Leukemia	JOSD1 →	+0.478	+3.411	.009	.003	3	2
BLOOD_Leukemia	HSDL1 →	+1.017	+3.120	<.001	.009	3	2
BLOOD_Leukemia	FBXL20 →	+0.481	+3.351	.004	.003	3	2
BLOOD_Leukemia	CSRNP2 →	+1.199	+3.228	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,372 associations by consensus.

GFRA4 by ZNF142 expression — PANCREAS

Explore this box plot interactively →