Across TCGA patient cohorts, ZNF140 mutation is significantly associated with the RNA expression of many other genes, with 1,018 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF140-associated genes across cancer lineages are MIR513C, SNORD115-21, and RNU6-164P. Each is linked with ZNF140 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF140-to-partner and partner-to-ZNF140 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF140→partner) and Y-score (partner→ZNF140) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR513C →	+0.517	+7.954	<.001	.008	3	2
BLCA	SNORD115-21 →	+0.432	+7.640	<.001	.009	3	2
LUSC	RNU6-164P →	+0.430	+6.309	<.001	.001	3	2
LUSC	C16orf97 →	+0.296	+5.625	<.001	.004	3	2
READ	CDRT15P8 →	+0.125	+5.421	<.001	.005	3	1
SKCM	MIR6718 →	+0.470	+5.797	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,018 associations by consensus.

Exploration

ZNF140 survival (RNA) · tumor vs normal (RNA) · all ZNF140 data types