ZNF14

Across TCGA patient cohorts, ZNF14 mutation is significantly associated with the RNA expression of many other genes, with 2,600 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF14-associated genes across cancer lineages are RN7SL578P, RNA5SP420, and PGBD4P2. Each is linked with ZNF14 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF14-to-partner and partner-to-ZNF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL578P grouped by ZNF14-low versus ZNF14-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF14→partner) and Y-score (partner→ZNF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL578P →	+0.172	+5.039	<.001	.008	3	3
UCEC	RNA5SP420 →	+0.351	+1.588	.001	.003	3	3
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	2
UCEC	MIR6801 →	+0.294	+1.398	.002	.005	3	2
UCEC	RPS29P32 →	+0.281	+1.792	<.001	.003	3	2
READ	FAM230J →	+0.026	+6.257	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,600 associations by consensus.

RN7SL578P by ZNF14 expression — READ

Explore this box plot interactively →