ZNF14

Across TCGA cell cohorts, ZNF14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,937 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF14-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, mRNA splicing, via spliceosome, and RNA splicing, via transesterification reactions. Each is linked with ZNF14 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF14-to-partner and partner-to-ZNF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile grouped by ZNF14-low versus ZNF14-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF14→partner) and Y-score (partner→ZNF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.083	+1.068	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	mRNA splicing, via spliceosome →	+0.083	+1.068	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions →	+0.084	+0.957	.001	.001	3	13
OVARY	Chromatin looping →	+0.102	+0.722	.001	.003	3	11
OVARY	Vesicle coating →	+0.082	+0.869	<.001	<.001	3	10
OVARY	Heterochromatin formation →	+0.062	+0.701	<.001	.004	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,937 associations by consensus.

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile by ZNF14 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →