Across TCGA patient cohorts, ZNF138 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF138-associated genes across cancer lineages are Annexin-1, EGFR_pY1068, and eIF4E. Each is linked with ZNF138 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF138-to-partner and partner-to-ZNF138 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF138→partner) and Y-score (partner→ZNF138) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.715	+2.827	<.001	.001	3	2
UCEC	EGFR_pY1068 →	-0.305	-1.847	<.001	.008	3	1
UCEC	eIF4E →	+0.183	+3.335	.018	.005	3	1
UCEC	FASN →	+0.331	+1.847	.022	.008	3	1
UCEC	FOXO3a_pS318_S321 →	-0.093	-1.896	.042	.015	3	1
UCEC	ACC1 →	+0.388	+3.598	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

ZNF138 survival (RNA) · tumor vs normal (RNA) · all ZNF138 data types