ZNF136

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF136 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF136-associated genes across cancer lineages are 14-3-3_beta, eEF2, and PRAS40_pT246. Each is linked with ZNF136 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF136-to-partner and partner-to-ZNF136 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF136→partner) and Y-score (partner→ZNF136) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.096-3.673.006.00132
UCECeEF2 →+0.297+2.000.016.03032
UCECPRAS40_pT246 →+0.120+1.183.044.04432
UCECCaspase-7-cleavedD198 →+0.616+2.926.002<.00132
UCECC-Raf →+0.144+1.678.003.02132
UCECCyclin-E2 →+0.147+1.594.011.02132
Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration