Across TCGA cell cohorts, ZNF136 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF136-associated genes across cancer lineages are GYS2, PLVAP, and CCDC54. Each is linked with ZNF136 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF136-to-partner and partner-to-ZNF136 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF136→partner) and Y-score (partner→ZNF136) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GYS2 →	+0.018	+4.467	<.001	.004	3	1
LARGE_INTESTINE	PLVAP →	+0.233	+3.426	<.001	.007	3	1
LARGE_INTESTINE	CCDC54 →	+0.130	+4.000	<.001	.001	3	1
LARGE_INTESTINE	CPLX4 →	+0.020	+3.807	.005	.001	3	1
LARGE_INTESTINE	SPINK9 →	+0.240	+3.115	<.001	.004	3	1
LARGE_INTESTINE	IQCF6 →	+0.188	+3.297	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ZNF136 survival (RNA) · tumor vs normal (RNA) · all ZNF136 data types