ZNF135

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF135 protein abundance is significantly associated with the RNA expression of many other genes, with 410 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF135-associated genes across cancer lineages are RASA4, RNF43, and ODAM. Each is linked with ZNF135 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF135-to-partner and partner-to-ZNF135 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF135 versus RASA4 in BRCA, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF135→partner) and Y-score (partner→ZNF135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARASA4 →+1.098+3.656<.001.00231
BRCARNF43 →+1.596+3.590.004.00431
BRCAODAM →+0.945+3.402<.001<.00131
BRCATLNRD1 →+1.374+3.656.001.00231
BRCANGRN →+1.624+3.656.005.00231
BRCALINC01342 →+1.453+3.590.007.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 410 associations by consensus.

ZNF135 vs RASA4 — BRCA

Per-sample scatter of ZNF135 vs RASA4 in BRCA (Pearson r = 0.95).

Explore this scatter interactively →

Exploration