ZNF135

Across TCGA patient cohorts, ZNF135 mutation is significantly associated with the RNA expression of many other genes, with 3,115 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF135-associated genes across cancer lineages are FAM90A12P, BNIP1, and OIP5. Each is linked with ZNF135 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF135-to-partner and partner-to-ZNF135 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM90A12P grouped by ZNF135-low versus ZNF135-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF135→partner) and Y-score (partner→ZNF135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	FAM90A12P →	+0.036	+3.816	<.001	.007	3	4
LUSC	BNIP1 →	+0.429	+2.608	.001	.006	3	4
UCEC	OIP5 →	+0.696	+2.284	<.001	<.001	3	4
UCEC	NCAPG →	+0.670	+3.470	<.001	.002	3	4
UCEC	ZNHIT3 →	+0.364	+2.490	.003	.001	3	3
UCEC	UBE2S →	+0.642	+2.828	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,115 associations by consensus.

FAM90A12P by ZNF135 expression — CESC

Explore this box plot interactively →