ZNF133

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF133 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF133-associated genes across cancer lineages are FOXR1, SCGB1C1, and IFNA14. Each is linked with ZNF133 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF133-to-partner and partner-to-ZNF133 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXR1 grouped by ZNF133-low versus ZNF133-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF133→partner) and Y-score (partner→ZNF133) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEFOXR1 →+0.105+4.222<.001.00731
SOFT_TISSUESCGB1C1 →+0.055+4.977<.001.00231
SOFT_TISSUEIFNA14 →+0.024+4.369<.001.00831
URINARY_TRACTPLSCR5 →+0.030+5.087<.001.00431
LARGE_INTESTINETRDN →+0.040+4.054<.001.00431
BLOOD_LymphomaBMP15 →+0.029+5.643<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

FOXR1 by ZNF133 expression — SOFT_TISSUE

Box plot of FOXR1 in ZNF133-low vs ZNF133-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration