ZNF132

Across TCGA cell cohorts, ZNF132 mutation is significantly associated with the RNA expression of many other genes, with 253 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF132-associated genes across cancer lineages are BPIFA1, HMGXB4, and RPL3. Each is linked with ZNF132 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF132-to-partner and partner-to-ZNF132 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFA1 grouped by ZNF132-low versus ZNF132-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF132→partner) and Y-score (partner→ZNF132) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFA1 →	+0.124	+2.688	<.001	.002	3	2
LARGE_INTESTINE	HMGXB4 →	+0.546	+3.212	.008	.006	3	1
LARGE_INTESTINE	RPL3 →	+0.489	+3.067	.007	.009	3	1
LARGE_INTESTINE	RSPH6A →	+0.096	+2.688	.003	.006	3	1
LARGE_INTESTINE	FAM149A →	+1.591	+3.212	<.001	.006	3	1
LARGE_INTESTINE	ULBP1 →	+1.547	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 253 associations by consensus.

BPIFA1 by ZNF132 expression — LARGE_INTESTINE

Explore this box plot interactively →