ZNF117

Across TCGA patient cohorts, ZNF117 mutation is significantly associated with the RNA expression of many other genes, with 4,138 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF117-associated genes across cancer lineages are UBE2V1P6, APOOP2, and LINC01872. Each is linked with ZNF117 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF117-to-partner and partner-to-ZNF117 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2V1P6 grouped by ZNF117-low versus ZNF117-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF117→partner) and Y-score (partner→ZNF117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	UBE2V1P6 →	+0.305	+4.925	<.001	.004	3	3
LUAD	APOOP2 →	+0.605	+4.575	<.001	.001	3	3
LUAD	LINC01872 →	+0.045	+4.285	.002	.003	3	3
COAD	MIR147A →	+0.488	+4.571	<.001	<.001	3	3
UCEC	IGHD4-17 →	+0.464	+1.884	<.001	.006	3	3
UCEC	KLF8 →	-0.507	-2.663	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,138 associations by consensus.

UBE2V1P6 by ZNF117 expression — READ

Explore this box plot interactively →