ZNF112

Across TCGA cell cohorts, ZNF112 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF112-associated genes across cancer lineages are CSN2, IFIT1B, and OR2J1. Each is linked with ZNF112 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF112-to-partner and partner-to-ZNF112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSN2 grouped by ZNF112-low versus ZNF112-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF112→partner) and Y-score (partner→ZNF112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CSN2 →	+0.031	+3.684	<.001	.006	3	1
LARGE_INTESTINE	IFIT1B →	+0.031	+3.823	.002	.006	3	1
LARGE_INTESTINE	OR2J1 →	+0.004	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TEX53 →	+0.098	+3.684	<.001	.006	3	1
LARGE_INTESTINE	ADAM7 →	+0.005	+3.930	<.001	.003	3	1
SKIN	MDFIC2 →	+0.155	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CSN2 by ZNF112 expression — LARGE_INTESTINE

Explore this box plot interactively →