ZNF106

Across TCGA patient cohorts, ZNF106 protein abundance is significantly associated with the RNA expression of many other genes, with 12,258 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF106-associated genes across cancer lineages are RFC4, MTBP, and USP39. Each is linked with ZNF106 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF106-to-partner and partner-to-ZNF106 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF106 versus RFC4 in LSCC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF106→partner) and Y-score (partner→ZNF106) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC4 →	+0.839	+0.239	<.001	.006	3	4
COAD	MTBP →	+0.852	+0.947	.001	.001	3	4
LSCC	USP39 →	+0.516	+0.249	<.001	<.001	3	4
COAD	RNPS1 →	+0.785	+1.007	.009	.001	3	4
LSCC	FAM83D →	+0.901	+0.249	.002	.002	3	3
LSCC	SUV39H1 →	+0.503	+0.302	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,258 associations by consensus.

ZNF106 vs RFC4 — LSCC

Explore this scatter interactively →