ZMYND19

Across TCGA patient cohorts, ZMYND19 mutation is significantly associated with the RNA expression of many other genes, with 67 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYND19-associated genes across cancer lineages are OR4M2, OR8A3P, and MIR3121. Each is linked with ZMYND19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYND19-to-partner and partner-to-ZMYND19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4M2 grouped by ZMYND19-low versus ZMYND19-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND19→partner) and Y-score (partner→ZMYND19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR4M2 →	+0.044	+8.055	<.001	.007	3	1
BLCA	OR8A3P →	+0.126	+5.411	.003	.005	3	1
BLCA	MIR3121 →	+0.463	+6.289	<.001	.001	3	1
BLCA	MTCO3P39 →	+0.085	+6.018	<.001	.002	3	1
BRCA	RNU2-57P →	+0.167	+8.055	<.001	.007	3	1
BRCA	MTND1P35 →	+0.094	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

OR4M2 by ZMYND19 expression — BRCA

Explore this box plot interactively →