ZMYND19

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZMYND19 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZMYND19-associated genes across cancer lineages are CCR8, ENPP7, and LRRC72. Each is linked with ZMYND19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYND19-to-partner and partner-to-ZMYND19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCR8 grouped by ZMYND19-low versus ZMYND19-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND19→partner) and Y-score (partner→ZMYND19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUECCR8 →+0.022+5.369<.001.00431
SOFT_TISSUEENPP7 →+0.006+5.369<.001.00431
SOFT_TISSUELRRC72 →+0.362+5.369<.001.00431
LARGE_INTESTINEWSCD2 →+0.232+3.660<.001.00531
LARGE_INTESTINECFHR2 →+0.038+4.022<.001.00631
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CCR8 by ZMYND19 expression — SOFT_TISSUE

Box plot of CCR8 in ZMYND19-low vs ZMYND19-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration