ZMYND15

Across TCGA cell cohorts, ZMYND15 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZMYND15-associated genes across cancer lineages are OR1L3, LILRB2, and ELOA3DP. Each is linked with ZMYND15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYND15-to-partner and partner-to-ZMYND15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by ZMYND15-low versus ZMYND15-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYND15→partner) and Y-score (partner→ZMYND15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	LILRB2 →	+0.019	+3.215	<.001	.007	3	1
LUNG_NSCLC_LUAD	ELOA3DP →	+0.111	+3.821	<.001	.007	3	1
LUNG_NSCLC_LUAD	LEUTX →	+0.033	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	UGT2A1 →	+0.435	+3.518	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR1L3 by ZMYND15 expression — SKIN

Explore this box plot interactively →