ZMYND10-AS1

Across TCGA pan-cancer cohorts, ZMYND10-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated ZMYND10-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher ZMYND10-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZMYND10-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and COAD show a favorable association.

MESO, KICH, and KIRC are the cancer types where ZMYND10-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	All	0.153	0.406	.002	90	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
KIRC	DFS	Tertile	III,IV	0.263	0.646	.006	75	view →
DLBC	DFS	Tertile	All	0.451	0.940	.004	36	view →
LGG	OS	Tertile	All	0.538	0.815	.001	33	view →
UCEC	OS	Tertile	All	0.780	0.650	.014	30	view →
BLCA	OS	Tertile	IV	0.285	0.605	.021	18	view →
SKCM	OS	Tertile	III,IV	0.170	0.424	.004	18	view →
ESCA	DFS	Tertile	All	0.232	0.773	.006	18	view →
UCS	OS	Tertile	All	0.241	0.694	.006	18	view →
TGCT	OS	Tertile	All	0.814	0.968	.006	18	view →
COAD	DFS	Tertile	III,IV	0.910	0.399	.038	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

ZMYND10-AS1–MESO (DFS)

Open the MESO breakdown →