ZMYND10-AS1

Across TCGA pan-cancer cohorts, ZMYND10-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ZMYND10-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where ZMYND10-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZMYND10-AS1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC and COAD are the cancer types where ZMYND10-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZMYND10-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.069	.009	4	view →
COAD	All	All	+0.039	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

ZMYND10-AS1–LUSC

Open the LUSC breakdown →