ZMYM6

Across TCGA pan-cancer cohorts, ZMYM6 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZMYM6 data layer compared with 26 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZMYM6 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ZMYM6 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, COAD, and LUAD are the cancer types where ZMYM6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.944	0.826	.020	22	view →
COAD	OS	Median	III,IV	0.140	0.792	<.001	15	view →
LUAD	OS	Median	All	0.141	0.788	<.001	12	view →
OV	DFS	Median	III,IV	0.218	0.533	.011	6	view →
LGG	DFS	Median	All	0.037	0.829	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZMYM6–UCEC (DFS)

Open the UCEC breakdown →