ZMYM6

Across TCGA patient cohorts, ZMYM6 mutation is significantly associated with the RNA expression of many other genes, with 4,961 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYM6-associated genes across cancer lineages are SASS6, KNL1, and CDCA5. Each is linked with ZMYM6 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZMYM6-to-partner and partner-to-ZMYM6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SASS6 grouped by ZMYM6-low versus ZMYM6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM6→partner) and Y-score (partner→ZMYM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SASS6 →	+0.368	+1.490	.005	.003	3	4
UCEC	KNL1 →	+0.541	+1.981	<.001	<.001	3	4
UCEC	CDCA5 →	+0.715	+1.513	<.001	<.001	3	4
SKCM	DHODH →	+0.324	+1.781	.003	.004	3	3
SKCM	DDX55 →	+0.485	+1.743	.001	.004	3	3
SKCM	NPRL2 →	+0.366	+3.076	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,961 associations by consensus.

SASS6 by ZMYM6 expression — UCEC

Explore this box plot interactively →