ZMYM6

Across TCGA patient cohorts, ZMYM6 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMYM6-associated genes across cancer lineages are p62 Lck ligand, ASNS, and eEF2. Each is linked with ZMYM6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZMYM6-to-partner and partner-to-ZMYM6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by ZMYM6-low versus ZMYM6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM6→partner) and Y-score (partner→ZMYM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.298	+1.906	.001	<.001	3	3
SKCM	ASNS →	+0.514	+2.000	.008	.031	3	2
UCEC	eEF2 →	+0.225	+1.700	.031	.040	3	2
UCEC	EGFR_pY1068 →	-0.212	-1.485	.003	.003	3	2
COAD	INPP4B →	-0.363	-3.000	.048	.035	3	2
UCEC	MEK1 →	+0.315	+1.523	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

p62 Lck ligand by ZMYM6 expression — UCEC

Explore this box plot interactively →