ZMYM6

Across TCGA cell cohorts, ZMYM6 mutation is significantly associated with the RNA expression of many other genes, with 77 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZMYM6-associated genes across cancer lineages are NCR1, IQCF5, and DCSTAMP. Each is linked with ZMYM6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYM6-to-partner and partner-to-ZMYM6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCR1 grouped by ZMYM6-low versus ZMYM6-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM6→partner) and Y-score (partner→ZMYM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	NCR1 →	+0.276	+4.906	<.001	.006	3	2
UPPER_AERODIGESTIVE_TRACT	IQCF5 →	+0.042	+4.357	<.001	.006	3	2
STOMACH	DCSTAMP →	+0.129	+3.432	.005	.008	3	2
URINARY_TRACT	VSIG4 →	+0.038	+4.321	<.001	.001	3	1
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	1
OESOPHAGUS	SPATA31E1 →	+0.166	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

NCR1 by ZMYM6 expression — OESOPHAGUS

Explore this box plot interactively →