ZMYM4

Across TCGA cell cohorts, ZMYM4 mutation is significantly associated with the RNA expression of many other genes, with 384 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZMYM4-associated genes across cancer lineages are MS4A10, GUCA2A, and GYPB. Each is linked with ZMYM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYM4-to-partner and partner-to-ZMYM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A10 grouped by ZMYM4-low versus ZMYM4-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM4→partner) and Y-score (partner→ZMYM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MS4A10 →	+0.007	+3.781	<.001	.001	3	2
BLOOD_Leukemia	GUCA2A →	+0.026	+3.969	<.001	.009	3	2
LUNG_NSCLC_LUSC	GYPB →	+0.080	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	OTC →	+0.033	+4.643	<.001	.008	3	1
STOMACH	SPINK14 →	+0.433	+5.285	<.001	.003	3	1
OVARY	PSG8 →	+1.203	+3.321	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 384 associations by consensus.

MS4A10 by ZMYM4 expression — OVARY

Explore this box plot interactively →