ZMYM2

Across TCGA cell cohorts, ZMYM2 mutation is significantly associated with the RNA expression of many other genes, with 532 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZMYM2-associated genes across cancer lineages are FSHB, MYF5, and GDF3. Each is linked with ZMYM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMYM2-to-partner and partner-to-ZMYM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FSHB grouped by ZMYM2-low versus ZMYM2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMYM2→partner) and Y-score (partner→ZMYM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	FSHB →	+0.046	+5.614	<.001	.002	3	1
CNS	MYF5 →	+0.756	+5.321	<.001	.005	3	1
LUNG_SCLC	GDF3 →	+0.013	+5.643	<.001	.002	3	1
BLOOD_Leukemia	GUCA1C →	+0.019	+4.384	<.001	.006	3	1
BLOOD_Leukemia	DIRAS2 →	+0.093	+4.087	<.001	.009	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.614	+3.169	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 532 associations by consensus.

FSHB by ZMYM2 expression — PANCREAS

Explore this box plot interactively →