ZMPSTE24

Across TCGA patient cohorts, ZMPSTE24 protein abundance is significantly associated with the RNA expression of many other genes, with 12,447 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMPSTE24-associated genes across cancer lineages are MYCBP, SRSF5, and ATP6V0B. Each is linked with ZMPSTE24 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZMPSTE24-to-partner and partner-to-ZMPSTE24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZMPSTE24 versus MYCBP in OV, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMPSTE24→partner) and Y-score (partner→ZMPSTE24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MYCBP →	+0.501	+0.412	.004	.001	3	5
HNSC	SRSF5 →	-0.575	-0.286	.006	.005	3	4
OV	ATP6V0B →	+0.591	+0.445	<.001	<.001	3	4
UCEC	TNXB →	-1.057	-0.571	<.001	<.001	3	4
HNSC	SLC9A9 →	-0.856	-0.324	<.001	.001	3	4
UCEC	ZNF728 →	-0.809	-0.645	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,447 associations by consensus.

ZMPSTE24 vs MYCBP — OV

Explore this scatter interactively →