ZMAT5

Across TCGA cell cohorts, ZMAT5 mutation is significantly associated with the mutation status of many other genes, with 557 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZMAT5-associated genes across cancer lineages are GGT1, SUN2, and RHBDD3. Each is linked with ZMAT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMAT5-to-partner and partner-to-ZMAT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGT1 grouped by ZMAT5-low versus ZMAT5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT5→partner) and Y-score (partner→ZMAT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GGT1 →	+4.736	+5.560	.003	.003	1	1
BLOOD_Leukemia	SUN2 →	+4.000	+5.050	.008	.008	1	1
BLOOD_Leukemia	RHBDD3 →	+4.736	+5.560	.003	.003	1	1
BLOOD_Leukemia	DPF1 →	+4.321	+5.285	.005	.005	1	1
BLOOD_Leukemia	PRICKLE3 →	+4.736	+5.560	.003	.003	1	1
BLOOD_Leukemia	CAPN1 →	+4.321	+5.285	.005	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 557 associations by consensus.

GGT1 by ZMAT5 expression — BLOOD_Leukemia

Explore this box plot interactively →