ZMAT3

Across TCGA patient cohorts, ZMAT3 mutation is significantly associated with the RNA expression of many other genes, with 1,239 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZMAT3-associated genes across cancer lineages are RPS15AP9, CYCSP26, and LINC02528. Each is linked with ZMAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMAT3-to-partner and partner-to-ZMAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS15AP9 grouped by ZMAT3-low versus ZMAT3-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT3→partner) and Y-score (partner→ZMAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RPS15AP9 →	+0.179	+4.724	<.001	.003	3	2
READ	CYCSP26 →	+0.209	+4.653	<.001	.007	3	2
UCEC	LINC02528 →	+0.398	+2.376	<.001	<.001	3	2
UCEC	RN7SKP60 →	+0.145	+2.257	.001	.006	3	2
UCEC	RN7SL248P →	+0.059	+3.137	<.001	.005	3	2
COAD	RNU6-1149P →	+0.639	+3.951	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,239 associations by consensus.

RPS15AP9 by ZMAT3 expression — READ

Explore this box plot interactively →