ZMAT2

Across TCGA patient cohorts, ZMAT2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,586 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZMAT2-associated genes across cancer lineages are BRD8, DDX46, and LIG1. Each is linked with ZMAT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZMAT2-to-partner and partner-to-ZMAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZMAT2 versus BRD8 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT2→partner) and Y-score (partner→ZMAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BRD8 →	+0.609	+0.232	<.001	<.001	2	7
LSCC	DDX46 →	+0.332	+0.229	<.001	<.001	3	6
UCEC	LIG1 →	+0.578	+0.182	.009	.008	3	5
GBM	LMNB1 →	+1.113	+0.353	<.001	<.001	3	5
HNSC	HROB →	+0.804	+0.133	<.001	.002	3	5
HNSC	ZNF740 →	+0.484	+0.187	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,586 associations by consensus.

ZMAT2 vs BRD8 — HNSC

Explore this scatter interactively →