ZMAT2

Across TCGA cell cohorts, ZMAT2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible ZMAT2-associated genes across cancer lineages are NRAP, KRTAP3-2, and TBC1D3. Each is linked with ZMAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZMAT2-to-partner and partner-to-ZMAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NRAP grouped by ZMAT2-low versus ZMAT2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZMAT2→partner) and Y-score (partner→ZMAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	NRAP →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KRTAP3-2 →	+0.943	+4.807	.001	.006	3	1
LARGE_INTESTINE	TBC1D3 →	+0.091	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

NRAP by ZMAT2 expression — BLOOD_Myeloma

Explore this box plot interactively →