Across TCGA cell cohorts, ZKSCAN5 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZKSCAN5-associated genes across cancer lineages are CCR8, BHLHA9, and GOLGA6L6. Each is linked with ZKSCAN5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZKSCAN5-to-partner and partner-to-ZKSCAN5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN5→partner) and Y-score (partner→ZKSCAN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	BHLHA9 →	+0.036	+5.977	<.001	.001	3	1
SOFT_TISSUE	GOLGA6L6 →	+0.013	+5.369	<.001	.004	3	1
OVARY	MYF5 →	+0.017	+4.807	<.001	.003	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	OR2M4 →	+0.108	+4.700	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Exploration

ZKSCAN5 survival (RNA) · tumor vs normal (RNA) · all ZKSCAN5 data types