ZKSCAN3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZKSCAN3 mutation is significantly associated with the RNA expression of many other genes, with 2,264 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZKSCAN3-associated genes across cancer lineages are SNORA40C, TAF9, and RN7SL248P. Each is linked with ZKSCAN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZKSCAN3-to-partner and partner-to-ZKSCAN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN3→partner) and Y-score (partner→ZKSCAN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCASNORA40C →+0.319+4.497<.001.00932
UCECTAF9 →+0.697+2.874<.001<.00132
UCECRN7SL248P →+0.048+2.847<.001.00832
UCECTMEM269 →+0.164+2.854.001.00232
LUADMIR8082 →+0.401+4.303<.001.00932
UCECAAGAB →+0.478+2.042<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,264 associations by consensus.

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