ZKSCAN1

Across TCGA patient cohorts, ZKSCAN1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,774 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZKSCAN1-associated genes across cancer lineages are ZNF3, TYW1, and PEX1. Each is linked with ZKSCAN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZKSCAN1-to-partner and partner-to-ZKSCAN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZKSCAN1 versus ZNF3 in UCEC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZKSCAN1→partner) and Y-score (partner→ZKSCAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF3 →	+0.870	+0.372	<.001	<.001	3	9
UCEC	TYW1 →	+0.663	+0.286	<.001	<.001	3	8
UCEC	PEX1 →	+0.698	+0.331	<.001	<.001	3	8
HNSC	ZSCAN21 →	+0.684	+0.332	<.001	<.001	3	8
UCEC	ZSCAN25 →	+0.647	+0.414	<.001	<.001	3	7
HNSC	AP4M1 →	+1.029	+0.413	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,774 associations by consensus.

ZKSCAN1 vs ZNF3 — UCEC

Explore this scatter interactively →