ZIK1

Across TCGA patient cohorts, ZIK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,655 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZIK1-associated proteins across cancer lineages are TRAP1, FERMT2, and MRPL49. Each is linked with ZIK1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZIK1-to-partner and partner-to-ZIK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZIK1 versus TRAP1 in OV, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZIK1→partner) and Y-score (partner→ZIK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRAP1 →	-0.430	-1.015	.002	.001	3	7
UCEC	FERMT2 →	+0.743	+0.636	<.001	.002	3	7
OV	MRPL49 →	-0.327	-0.944	.003	.003	3	6
COAD	ZSCAN18 →	+1.275	+0.548	.003	.009	3	6
UCEC	PRKG1 →	+0.518	+0.392	<.001	.004	3	6
LSCC	MRPS5 →	-0.391	-0.892	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,655 associations by consensus.

ZIK1 vs TRAP1 — OV

Explore this scatter interactively →