ZHX1

Across TCGA patient cohorts, ZHX1 mutation is significantly associated with the RNA expression of many other genes, with 4,452 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZHX1-associated genes across cancer lineages are RNU6-1067P, RNA5SP412, and LINC02167. Each is linked with ZHX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZHX1-to-partner and partner-to-ZHX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1067P grouped by ZHX1-low versus ZHX1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZHX1→partner) and Y-score (partner→ZHX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-1067P →	+0.456	+4.569	<.001	.005	3	3
UCEC	RNA5SP412 →	+0.632	+2.143	<.001	<.001	3	2
UCEC	LINC02167 →	+2.751	+3.746	<.001	<.001	3	2
READ	MTND1P26 →	+0.179	+5.421	<.001	.005	3	2
READ	RNU7-43P →	+0.648	+6.257	<.001	.001	3	2
UCEC	QRFP →	+0.315	+1.818	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,452 associations by consensus.

RNU6-1067P by ZHX1 expression — CESC

Explore this box plot interactively →