ZHX1

Across TCGA cell cohorts, ZHX1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,149 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ZHX1-associated genes across cancer lineages are PPIG, METTL8, and CHEK2. Each is linked with ZHX1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZHX1-to-partner and partner-to-ZHX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZHX1 versus PPIG in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZHX1→partner) and Y-score (partner→ZHX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PPIG →	+0.710	+0.672	.002	.001	3	8
KIDNEY	METTL8 →	+0.990	+0.444	.002	.009	3	7
LUNG_NSCLC_LUSC	CHEK2 →	+1.123	+0.850	.004	.006	3	5
STOMACH	SUMO1 →	+0.623	+0.768	.002	.001	3	5
LUNG_SCLC	PMS1 →	+0.602	+0.610	.003	.006	3	5
SOFT_TISSUE	RFXANK →	+0.839	+0.973	.003	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,149 associations by consensus.

ZHX1 vs PPIG — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →