ZFYVE9

Across TCGA cell cohorts, ZFYVE9 mutation is significantly associated with the RNA expression of many other genes, with 223 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZFYVE9-associated genes across cancer lineages are TSHB, OR2T6, and KRTAP9-1. Each is linked with ZFYVE9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZFYVE9-to-partner and partner-to-ZFYVE9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSHB grouped by ZFYVE9-low versus ZFYVE9-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE9→partner) and Y-score (partner→ZFYVE9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TSHB →	+0.055	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	OR2T6 →	+0.009	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP9-1 →	+0.032	+4.662	<.001	.003	3	1
BLOOD_Lymphoma	SPATS1 →	+0.646	+3.714	<.001	.006	3	1
LARGE_INTESTINE	CBY1 →	+0.625	+3.451	.001	.002	3	1
LARGE_INTESTINE	L3MBTL2 →	+0.533	+3.364	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 223 associations by consensus.

TSHB by ZFYVE9 expression — BLOOD_Lymphoma

Explore this box plot interactively →