ZFYVE28

Across TCGA patient cohorts, ZFYVE28 mutation is significantly associated with the RNA expression of many other genes, with 3,532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZFYVE28-associated genes across cancer lineages are GMNN, UBAC1, and FN3KRP. Each is linked with ZFYVE28 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZFYVE28-to-partner and partner-to-ZFYVE28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMNN grouped by ZFYVE28-low versus ZFYVE28-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE28→partner) and Y-score (partner→ZFYVE28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GMNN →	+0.635	+2.826	.003	.001	3	3
SKCM	UBAC1 →	+0.362	+3.623	.003	.001	3	3
SKCM	FN3KRP →	+0.393	+2.446	.005	.001	3	3
SKCM	NARF →	+0.445	+1.925	.006	.009	3	3
SKCM	UBE2T →	+0.598	+1.938	.005	.009	3	3
LUAD	DUTP3 →	+0.041	+4.333	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,532 associations by consensus.

GMNN by ZFYVE28 expression — SKCM

Explore this box plot interactively →