ZFYVE27

Across TCGA patient cohorts, ZFYVE27 protein abundance is significantly associated with the RNA expression of many other genes, with 6,322 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZFYVE27-associated genes across cancer lineages are PDZD8, TM9SF3, and NKD1. Each is linked with ZFYVE27 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZFYVE27-to-partner and partner-to-ZFYVE27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZFYVE27 versus PDZD8 in UCEC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZFYVE27→partner) and Y-score (partner→ZFYVE27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDZD8 →	+0.636	+0.437	<.001	<.001	3	6
LSCC	TM9SF3 →	+0.501	+0.317	<.001	<.001	3	5
UCEC	NKD1 →	+2.428	+0.834	<.001	<.001	3	4
LSCC	CACUL1 →	+0.452	+0.294	<.001	<.001	3	4
UCEC	VWA2 →	+1.691	+0.617	<.001	<.001	3	4
UCEC	BTRC →	+0.391	+0.542	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,322 associations by consensus.

ZFYVE27 vs PDZD8 — UCEC

Explore this scatter interactively →